肠道菌群与缺血性脑卒中相关研究进展

肠道菌群是目前国内外学者研究的热点问题,缺血性脑卒中后肠道菌群的结构及组成会发生改变,可能会对卒中后人群的生命健康产生威胁。肠道菌群通过增加促炎细胞因子的产生及肠道通透性等机制影响疾病的进展。通过菌群与卒中相关炎症反应、缺血性脑卒中后患者肠道菌群的变化、菌群对脑卒中并发症的影响和目前肠道菌群用于临床治疗的可能性对肠道菌群与缺血性脑卒中的研究进展进行综述。在临床诊治过程中,应考虑到肠道菌群的影响,以免影响疾病的诊断和治疗。

Developments on intestinal flora and ischemic stroke

Intestinal flora is currently a hot issue studied by scholars around the world. The structure and composition of intestinal flora will change after ischemic stroke, which may threaten the life and health of people after stroke. Intestinal flora affects the progression of the disease by increasing the production of pro-inflammatory cytokines and intestinal permeability. Through the flora and stroke-related inflammatory response, the changes in the intestinal flora of patients after ischemic stroke, the impact of the flora on the complications of stroke, and the possibility of the current intestinal flora for clinical treatment, the progress of the intestinal flora and ischemic stroke were reviewed. In the process of clinical diagnosis and treatment, the influence of intestinal flora should be considered so as not to affect the diagnosis and treatment of the disease.