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Stelazine-induced pigmentation
Authors:C. BUCKLEY  V. THOMAS  J. LEWIN  D. HARRIS  M.H.A. RUSTIN
Affiliation:Department of Dermatology, The Royal Free Hospital, Pond St, Hampstead, London, UK;Department of Histopathology, The Royal Free Hospital, Pond St, Hampstead, London, UK
Abstract:A case of a West Indian patient is reported who developed abnormal blue-grey pigmentation on exposed areas of skin following treatment with low dose stelazine. Oculocutaneous melanosis is a well-recognized side-effect of prolonged phenothiazine treatment. In this condition the areas of skin exposed to sunlight develop a violaceous, blue-grey or slate-grey colour in more severe cases. These characteristic changes are rarely seen now. We describe the case of a patient who developed pigmentation while taking a low dose of stelazine for 5 years.
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