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自乳化药物传递系统的研究进展
引用本文:冯耀荣,程巧鸳,李范珠.自乳化药物传递系统的研究进展[J].国外医学(药学分册),2007,34(4):280-284.
作者姓名:冯耀荣  程巧鸳  李范珠
作者单位:浙江中医药大学药学院,杭州310053
摘    要:本文对近几年国内外有关自乳化药物传递系统的特点、吸收机制、组成、影响因素及其在药剂学方面的应用进行了归纳和分析。自乳化药物传递系统可显著地提高难溶性或亲脂性药物口服生物利用度,具有广阔的发展前景。

关 键 词:自乳化药物传递系统  吸收机制  表面活性剂  生物利用度
文章编号:1674-0440(2007)04-0280-05
收稿时间:2006-12-08

Self-emulsifying drug delivery systems:a recent development
FENG Yao-rong, CHENG Qiao-yuan, LI Fan-zhu.Self-emulsifying drug delivery systems:a recent development[J].Foreign Medical Sciences(Section of Pharmarcy),2007,34(4):280-284.
Authors:FENG Yao-rong  CHENG Qiao-yuan  LI Fan-zhu
Abstract:A lot of recent literature about self-emulsifying drug delivery systems(SEDDS) were cited,and the characteristics,absorption mechanisms,formulation ingredients,influencing factors and the recent application research were analyzed and summarized.The SEDDS can dramatically improve the bioavailability of poorly water soluble or lipophilic drugs by oral administration.SEDDS will have a good developmental potential.
Keywords:self-emulsifying drug delivery systems  absorption mechanisms  surfactants  bioavailability
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