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| 培多普利和依那普利治疗原发性高血压的疗效比较 | |
| 引用本文： | 刘爱香,徐冰,李有俊.培多普利和依那普利治疗原发性高血压的疗效比较[J].临床医药实践,2007,16(10):967-968. |
| 作者姓名： | 刘爱香 徐冰 李有俊 |
| 作者单位： | 1. 山西医科大学第二医院,山西,太原,030001 2. 山西省军区门诊部,山西,太原,030013 3. 孝义市兑镇医院,山西孝义,032302 |
| 摘 要： | 目的:比较培多普利和依那普利治疗原发性高血压的疗效和安全性。方法:将76例高血压患者随机分成两组:培多普利组和依那普利组,疗程24周,观察治疗前后血压的变化。结果:两药均能显著降低血压,培多普利有效率为89.5%,依那普利有效率为81.5%,两者差异无显著性。培多普利的收缩压和舒张压的降压谷/峰比值均大于依那普利。结论:对原发性高血压,培多普利是一种有效、安全且易耐受的降压药,每日1次能维持24 h降压效应。 |
| 关 键 词： | 培多普利 依那普利 高血压病 |
| 文章编号： | 1671-8631(2007)10-0967-02 |
| 修稿时间： | 2007年4月24日 |
Comparison of perindopril and enalapril in the treatment of essential hypertension |
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| LIU Ai-xiang,XU Bing,LI You-jun.Comparison of perindopril and enalapril in the treatment of essential hypertension[J].Proceeding of Clinical Medicine,2007,16(10):967-968. | |
| Authors: | LIU Ai-xiang XU Bing LI You-jun |
| Abstract: | Objective:To compare the efficacy and safety of perindopril and enalapril in the treatment of essential hypertension.Methods:Sixtysix cases with essential hypertension were divided randomly into two groups:perindopril and enalapril.Treatment lasted for 24 weeks.Parameters of blood pressure was measured before and after treatment.Results:Blood pressure were significantly reduced in both groups.There was no significant difference in responder rates between perindopril treated patients(89.5%)and patients taking enalapril(81.5%).The trough to peak ratios of systolic and diastolic blood pressures of perindopril were greater than that of enalapril.Conclusion:Perindoprilonce daily is effective,safe and well tolerated in hypertensihe patients. |
| Keywords: | perindopril enalapril hypertension |
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