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Structural elucidation of fritillahupehin from bulbs of Fritillaria hupehensis Hsiao et K.C. Hsia
Authors:Zhang Yong-Hui  Ruan Han-Li  Pi Hui-Fang  Wu Ji-Zhou  Sun Han-Dong  Fujita Tetsuro
Institution:  a Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China b Kunming Institute of Botany, Kunming, China c Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan
Abstract:A novel diterpenoid ester, fritillahupehin (1) and three known fatty acids, palmitic acid (2), lignoceric acid (3) and azelaric acid (4), have been isolated from the bulbs of Fritillaria hupehensis Hsiao et K.C. Hsia. The structure of fritillahupehin has been established to be ent-kauran-16β-yl lignocerate by means of spectroscopic and chemical evidence. Compounds 2-4 were isolated from Fritillaria sp. for the first time.
Keywords:Fritillaria hupehensis  Diterpenoid ester  Fritillahupehin
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