| 同种骨基质明胶及无机骨粉对骨缺损修复的影响 |
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| 引用本文： | 李天方 莫东旭. 同种骨基质明胶及无机骨粉对骨缺损修复的影响[J]. 河南医学研究, 1995, 4(4): 304-307 |
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| 作者姓名： | 李天方 莫东旭 |
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| 作者单位： | 河南省人民医院骨科，西安医科大学骨病研究所 |
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| 摘 要： | 在大鼠双侧尺骨中段制成５ｍｍ的骨缺损，分别用骨基质明胶颗粒、骨基质明胶颗粒与无机骨粉的混合物充填骨缺损，术后分期取材，进行骨组织病理学及形态计量学分析，结果发现：骨基质明胶颗粒具有良好的骨诱导活性，在８周内可修复缺损；而用骨基质明胶与无机骨粉混合物充填骨缺损者，由于无机骨粉引起的异物反应，影响了局部诱导成骨及骨缺损的修复。
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| 关 键 词： | 骨基质明胶，无机骨粉，骨诱导，骨缺损，骨形态计量 |
M0RPHOMETRIC STUDY T0 THE EFFECT OF HOMOGENEOUS B0NE MATRIX GELATINE AND DE0RGANIFIED B0NE 0N THE HEALING 0F B0NE DEFECT |
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| Li Tian-fang Mo Dong-xu. M0RPHOMETRIC STUDY T0 THE EFFECT OF HOMOGENEOUS B0NE MATRIX GELATINE AND DE0RGANIFIED B0NE 0N THE HEALING 0F B0NE DEFECT[J]. Henan Medical Research, 1995, 4(4): 304-307 |
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| Authors: | Li Tian-fang Mo Dong-xu |
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| Abstract: | mm defects were made in the middle ulna of Wistar rats bilaterally. Thesedefects were filled with bone matrix gelatin (BMG)and the mixture of BMG and deorgani-fied bone(DOB)respectively.Postoperative histopathologic and morphometric analysis re-vealed that BMG had satisfactory inductive activity and it could repair defect within 8 weeks.Because of foreign body reaction of DOB influencing local inductive bone formation,defectscouldn′t be repaired by the mixture of DOB and BMG. |
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| Keywords: | bone matrix gelatine deorganified bone bone induction bone defect mor-phometry. |
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