老年恶性胃肠肿瘤临床病理特征及术后并发症相关因素分析

目的]分析老年恶性胃肠肿瘤患者临床病理特征及术后并发症发生情况.方法]本院进行手术治疗的80例老年(年龄＞65岁)恶性胃肠肿瘤患者按术后有无并发症分为并发症组(n =26)与无并发症组(n=54),比较分析患者临床病理特点及术后并发症相关影响因素.结果]①80患者中,26例术后出现并发症,并发症发生率为32.50％(26/80),以切口感染、肺部感染、心血管病发生率最高,其次为肝肾功能异常、吻合口瘘;②术后发生并发症组男性所占病例高于无并发症组,且其手术时间、年龄均大于无并发症组,两组合并症、TNM分期、病理分化程度、淋巴结清扫情况、淋巴结转移发生率等相比较差异均有显著性(P＜0.05);③多因素回归分析显示:年龄、手术时间、术前合并症、淋巴结清扫类型、病理分化程度是影响胃肠道恶性肿瘤患者术后并发症发生的独立危险因素(P＜0.05).结论]年龄、性别、病理分化程度、淋巴结清扫、术前合并症均为影响老年胃肠道恶性肿瘤患者术后并发症发生率的独立危险因素,临床应积极控制相关危险因素.

Analysis of Pathological Features and Postoperative Complications in 80 Elderly Patients with Malignant Gastrointestinal Tumor

Objective]To analyze the clinical pathological features and postoperative complications in elderly patients with malignant gastrointestinal tumors.Methods]A retrospective analysis of clinical data was carried out on 80 elderly (age ＞65 years) patients with malignant gastrointestinal tumors who received surgery in our hospital.According to the occurence of postoperative complications,patients were divided into the complication group (n =26) and non-complication group (n =54).Clinical pathological characteristics of patients between the two groups were analyzed to explore the related influencing factors of postoperative complications.Results]① In the 80 elderly patients with malignant gastrointestinal tumor,26 patients had postoperative complications (32.50 ％).The complications were mainly infections of the incisional wound,pulmonary infections,and angiocardiopathy.Other complications included liver and kidney dysfunction and anastomotic leakage.② Male patients made up a significantly higher proportion of the postoperative complications group,and their ()tive timc and age were significantly greater than non-complication group.There were significant differences in frequency of complications,TNM staging,pathologic differentiation,lymph nodes cleanliness,and lymphatic metastasis between the two groups (P ＜0.05).③ Multivariate regression analysis showed that age,operation time,preoperative complications,lymph node dissection type,and pathologic differentiation were all independent risk factors which influenced postoperative complications of patients with malignant gastrointestinal tumor (P ＜0.05).Conclusion]Age,gender,pathologic differentiation,lymph node dissection,and preoperative complications are independent risk factors which influence postoperative complications of elderly patients with malignant gastrointestinal tumor-indicating preparation for prevention and treatment of complications in clinic.