| 细胞粘附分子CD_(62)P在直肠癌中的表达及其临床意义 |
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| 引用本文： | 赵铁军,王贵和. 细胞粘附分子CD_(62)P在直肠癌中的表达及其临床意义[J]. 肿瘤研究与临床, 2001, 0(2) |
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| 作者姓名： | 赵铁军 王贵和 |
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| 作者单位： | 安徽省铜陵市第一人民医院!安徽铜陵244000 |
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| 摘 要： | 目的 :探讨细胞粘附分子 CD6 2 P在直肠癌中的表达及与其生物学行为的关系。方法 :采用 SP免疫组化方法观察了 CD6 2 P在 40例直肠癌中的表达情况。结果 :非癌肠组织未见 CD6 2 P表达 ,直肠癌组织中 CD6 2 P阳性表达率为 6 5 % (2 6 / 40 )。在浸润型直肠癌 ,浸透浆膜及发生淋巴转移直肠癌中 CD6 2 P表达显著增强 (P<0 .0 1)。结论 :CD6 2 P与直肠癌的浸润及淋巴转移关系密切 ,其表达的检测对评估直肠癌的浸润及淋巴转移程度和分析病期有重要意义
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| 关 键 词： | 直肠肿瘤 细胞粘附分子 免疫组化 |
THE SIGNIFICANCE OF CELL ADHESION MOLECULES CD_(62) P EXPRESSION IN RECTAL CANCER |
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| ZHAO Tie jun,WANG Gui he The People''''s Hospital of Tonglin City. THE SIGNIFICANCE OF CELL ADHESION MOLECULES CD_(62) P EXPRESSION IN RECTAL CANCER[J]. Cancer Research and Clinic, 2001, 0(2) |
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| Authors: | ZHAO Tie jun WANG Gui he The People''''s Hospital of Tonglin City |
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| Abstract: | Objective:To study the relationshop between cell adhesion molecules CD 62 P expression and biological behavior of rectal cancer.Methods:The levels of CD 62 P expression was observed in 40 cases of rectal cancer using SP immunohistochemistry staining.Rusults:The rate of CD 62 P expression was 65%(26/40) in rectal cancer.CD 62 P expression was more intensive in rectal cancer with infiltrated serosa and lymph node metastasis ( P <0.01).Conclusion:CD 62 P expression was correlate with infiltrated lymph node metastasis behavior of rectal cancer.The examination of Cd 62 P expression in rectal cancer may have an important value in evaluating infiltrated lymph node metastasis intensity and stage of rectal cancer. |
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| Keywords: | Rectal carcinoma Cell adhesion molecules Immunohistochemistry |
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