| Correlation of neuron specific enolase serum concentration and prognosis hi patients with severe head injury |
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| 引用本文： | 占世坤,李宁,蔡俞,沈建康. Correlation of neuron specific enolase serum concentration and prognosis hi patients with severe head injury[J]. 中国组织工程研究与临床康复, 2003, 0(2) |
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| 作者姓名： | 占世坤 李宁 蔡俞 沈建康 |
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| 作者单位： | Department cf Neurosurgery，Ruijin Hospital，Shanghai Second Medical University，Department cf Neurosurgery，Ruijin Hospital，Shanghai Second Medical University，Department cf Neurosurgery，Ruijin Hospital，Shanghai Second Medical University，Department cf Neurosurgery，Ruijin Hospital，Shanghai Second Medical University Shanghai 200025，China，Shanghai 200025，China，Shanghai 200025，China，Shanghai 200025，China |
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| 摘 要： | AIM: To eluciate the role of neuron specific enolase(NSE) in predicting prognosis after severe head injury. METHODS: 30 patients with severe head injury were involved into this study, ranging from 26 to 64 years old. Concentration of NSE in serum was measured in all cases within 12 hours after head injury. And prognosis of all patients were evaluated by COS. RESULTS: The concentration of NSE in serum of both groups, with good or poor outcome, were higher than normal group. The concentrations within 12 hours after head injuries had a close relationship with the prognosis. As a serum marker to assess the prognosis, NSE had high positive prediction ratio. CONCLUSION: The finding suggested that NSE may be a promising predictor for assessing the prognosis after severe head injury.
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Correlation of neuron specific enolase serum concentration and prognosis hi patients with severe head injury |
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| Zhan Shikun,LI Ning,Cai Yu,ShenJiankang. Correlation of neuron specific enolase serum concentration and prognosis hi patients with severe head injury[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2003, 0(2) |
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| Authors: | Zhan Shikun LI Ning Cai Yu ShenJiankang |
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| Affiliation: | Zhan Shikun,LI Ning,Cai Yu,ShenJiankang,Department of Neurosurgery,Ruijjn Hospital,Shanghai Second Medical University,Shanghai 200025,China |
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| Abstract: | AIM: To eluciate the role of neuron specific enolase(NSE) in predicting prognosis after severe head injury. METHODS: 30 patients with severe head injury were involved into this study, ranging from 26 to 64 years old. Concentration of NSE in serum was measured in all cases within 12 hours after head injury. And prognosis of all patients were evaluated by COS. RESULTS: The concentration of NSE in serum of both groups, with good or poor outcome, were higher than normal group. The concentrations within 12 hours after head injuries had a close relationship with the prognosis. As a serum marker to assess the prognosis, NSE had high positive prediction ratio. CONCLUSION: The finding suggested that NSE may be a promising predictor for assessing the prognosis after severe head injury. |
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| Keywords: | phosphopyruvate hydratase/immunology brain injuries prognosis |
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