| The influence of modified electroco nvulsive therapy on serum interleukin-6in schizophrenic patients |
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| 作者姓名： | 杜宝国 吕路线 赵洪祖 李红 张四高 |
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| 作者单位： | Gerontology Department，Second Affiliated Hosp ital，Xinxiang Medical College，Gerontology Department，Second Affiliated Hosp ital，Xinxiang Medical College，Gerontology Department，Second Affiliated Hosp ital，Xinxiang Medical College，Gerontology Department，Second Affiliated Hosp ital，Xinxiang Medical College，Gerontology Department，Second Affiliated Hosp ital，Xinxiang Medical College in xiang453002，Henan Province，China，in xiang453002，Henan Province，China，in xiang453002，Henan Province，China，in xiang453002，Henan Province，China，in xiang453002，Henan Province，China |
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| 摘 要： | INTRODUCTIONRecentlythestudyonthefunctionofcytokineinschizophreniaincreased．Somestudiesreportedthatthemajortranquilizermightrealizeitseffectsoncytokinethroughinhibitionofinterleukin－６（IL－６andrealizeitsimmuneinhibitionfunction犤１犦．Livingqualityofschizophrenicpatientsislow犤２犦，modifiedelectroconvulsivetherapycanameioratetheirlivingqualityeffectively．ButtherewerefewresearchesotheinfluenceofMECTonIL－６．ThisexperimentaimedtoexplorethinfluenceofMECTonserumIL－６inschizophre…
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The influence of modified electroco nvulsive therapy on serum interleukin-6in schizophrenic patients |
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| Du Baoguo,Lu Luxian,Zhao Hongzu,Li Hong,Zhang Sigao,Gerontology.The influence of modified electroco nvulsive therapy on serum interleukin-6in schizophrenic patients[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2003(3). |
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| Authors: | Du Baoguo Lu Luxian Zhao Hongzu Li Hong Zhang Sigao Gerontology |
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| Institution: | Du Baoguo,Lu Luxian,Zhao Hongzu,Li Hong,Zhang Sigao,Gerontology Department,Second Affiliated Hosp ital,Xinxiang Medical College,Xin xiang453002,Henan Province,China |
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| Abstract: | AIM:T o explore the influence of modified e lectroconvulsive therapy on serum interleukin-6in schizophrenic patients.METHOD:T esting change of serum IL-6in 60cases treated with MECT and60control cases treated with clozap ine therapy by ELISA method.RESULTS:Serum IL-6level before treatment of both groups was positive related to S APS;serum IL-6level wasn' t related to BPRS total score,factor score and SA NS total fractions.IL-6level of clo zapine therapy group decrease apparently a fter treatment,and IL-6level was ap par-ently positive related to anxious depressed factor of BPRS;but there was no apparent difference in IL-6level of MECT group between before and after treatment.CONCLUSION:To schizophrenic patients,clozapi ne can take ef-fects of immune inhibit through inhi biting serumIL-6;MECT may have different mechanism. |
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| Keywords: | SUBJECT WORDS:schizophrenia /immunlolgy interleukin-6 schizophreni-a /therapy |
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