Effect of the antibody of brain-derived neurotrophic factor on the rat with ischemic injury from obstruction of middle cerebral artery |
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作者姓名: | 陈英辉 王根发 陈兴华 姚革 陈伟 周永炜 |
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作者单位: | Department of Neurology,Affiliated Xinhua Hospital of Second Medical University in Shanghai,Department of Neurology,Affiliated Xinhua Hospital of Second Medical University in Shanghai,Department of Neurology,Affiliated Xinhua Hospital of Second Medical University in Shanghai,Department of Neurology,Affiliated Xinhua Hospital of Second Medical University in Shanghai,Department of Neurology,Affiliated Xinhua Hospital of Second Medical University in Shanghai,Department of Neurology,Affiliated Xinhua Hospital of Second Medical University in Shanghai Shanghai 200092,China,Shanghai 200092,China,Shanghai 200092,China,Shanghai 200092,China,Shanghai 200092,China,Shanghai 200092,China |
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摘 要: | INTRODUCTIONCorticalmicroinjectionofspecificBDNFantibodyhadbeenappliedtoobservetheeffectofBDNFoncerebralischemiaintheratemodelwithlocalcerebralischemic-reperfusioninjury犤1-3犦.MATERIALSANDMETHODSMaterialsWistermalerats230-260gweresupportedbyanimalcenterinFudanUniversity.Theratsweredividedintotwogroupsrandomly:BDNFantibodyinjection(A)groupandcontrol(B)group.TheratsingroupAwereinjectedwith3μlBDNFantibody(rabbits-anti-rats1:100SantaCruzproduction),andtheratsingroupBwereinj…
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