Characterization of extended-spectrum beta-lactamases, antimicrobial resistance genes, and plasmid content in Escherichia coli isolates from different sources in Rio de Janeiro, Brazil |
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| Authors: | Queiroz Mara L P Antunes Patrícia Mourão Joana Merquior Vânia L C Machado Elisabete Peixe Luísa Vieira |
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| Affiliation: | Departamento de Microbiologia, Imunologia e Parasitologia, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, 20551-030 Rio de Janeiro, Brazil. |
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| Abstract: | We analyse the diversity of extended-spectrum beta-lactamases (ESBLs), antibiotic resistance genes, and plasmid content among Escherichia coli from a community and a hospital setting in Rio de Janeiro, Brazil. ESBL producers (CTX-M-2, CTX-M-9, CTX-M-59) belonged to different phylogroups/sequence types, and bla(CTX-M) were identified in IncA/C plasmids, reinforcing the possible intraplasmid evolution of bla(CTX-M-59) from bla(CTX-M-2) and the implication of IncA/C on bla(CTX-M) spread. |
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| Keywords: | Escherichia coli ESBLs CTX-M-2 CTX-M-9 CTX-M-59 IncA/C |
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