高乌甲素用于多发肋骨骨折胸痛的临床观察

目的观察高乌甲素用于多发肋骨骨折胸痛的镇痛疗效和安全性。方法选择80例多发肋骨骨折病人，随机分成两组，高乌甲素（治疗组）和哌替啶（对照组）各40例。VAS评分5分以上者镇痛治疗，记录两组药物的镇痛效果、镇痛起效时间和维持时间，并统计两组药物的副作用。结果两组间镇痛疗效的比较差异无显著性（P〉0．05）；副作用发生情况的比较，治疗组副作用明显比对照组副作用少，差异显著（P〈0．05）。结论高乌甲素用于多发肋骨骨折胸痛镇痛安全有效，值得临床推广应用。

Analgesic Effect of Lappaconitine on Chest-wall Pain with Multiple Rib Fractures

Objective To observe the analgesic effect and safety, of lappaconitine on chest-wall pain with multiple rib fractures. Methods 80 patients with chest-wall pain after multiple rib fractures were randomly divided into two groups with 40 patients each. They were treated with lappaconitine or pethidine when the score preponderated over 5 in VAS score. Tracked record the analgesic effect, intial time and persisting time of the analgesic action, and registered side-effect between the two groups. Results There were not differences of analgesic effect between the two groups （P〉 0.05 ）. The incidence rate of adverse reaction in treatment group was significantly less compared with other group（P〈 0.05）. Conclusion Lappaconitine was safe and effective on chest-wall pain with multiple rib fractures. And it may be worthy of extending clinical application.