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B7-H4与糖尿病关系的研究进展
引用本文:汝燕,李素梅.B7-H4与糖尿病关系的研究进展[J].安徽医药,2011,15(11):1332-1334.
作者姓名:汝燕  李素梅
作者单位:安徽医科大学附属省立医院内分泌科,安徽,合肥,230001;安徽医科大学附属省立医院内分泌科,安徽,合肥,230001
摘    要:1型糖尿病(Type 1 diabetes mellitus,T1DM)是一种T细胞介导的胰岛β细胞选择性破坏的自身免疫病,2型糖尿病(Type2 diabetes mellitus,T2DM)存在一种慢性的低度炎症状态,阐明免疫系统活化机制对糖尿病(DM)及相关代谢紊乱防治具有十分重要的意义。该文探讨糖尿病患者共刺激因子B7-H4的表达及其与疾病发生发展的关系,并为寻找糖尿病肾病的合理的诊断与治疗提供新的途径。

关 键 词:糖尿病  B7-H4  糖尿病肾病

Relationship between B7-H4 and diabetes
RU Yan,LI Su-mei.Relationship between B7-H4 and diabetes[J].Anhui Medical and Pharmaceutical Journal,2011,15(11):1332-1334.
Authors:RU Yan  LI Su-mei
Institution:(Dept of Endocrinology,Anhui Provincial Hospital Affiliated to Anhui Medical University,Hefei 230001)
Abstract:Type 1 diabetes mellitus is an autoimmune disease of selective destruction of pancreatic β cell mediated by T cell,while type 2 diabetes mellitus has recognized the existence of a state of chronic low-grade inflammation.Illuminating the mechanisms of immune system activation is enormously significant in the prevention and treatment of diabetes and related metabolic disorder.This article explores the expression of co-stimulating factor B7-H4 and its relationship with the occurrence and development of diabetes mellitus,then find a new way for reasonable diagnosis and treatment of diabetic nephropathy.
Keywords:diabetes mellitus  B7-H4  diabetic nephropathy
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