| 低分子RNA抑制ConA与J6－1细胞膜受体结合的研究 |
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| 引用本文： | 毕富勇,陆进明. 低分子RNA抑制ConA与J6－1细胞膜受体结合的研究[J]. 皖南医学院学报, 1994, 0(3) |
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| 作者姓名： | 毕富勇 陆进明 |
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| 作者单位： | 附属弋矶山医院 |
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| 摘 要： | 提取Ｂｒｕｋｉｔｔ淋巴瘤（Ｎａｍａｌｖａ）细胞低分子ＲＮＡ与Ｊ６－１细胞悬液培养７２小时，掺入Ｆｒｒｃ标记的ＣｏｎＡ，于荧光显微镜下观察膜荧光细胞总数和帽状细胞数。结果显示实验组帽状细胞数明显减少并呈剂量依赖关系。提示低分子ＲＮＡ对白血病细胞增殖的抑制是通过作用于细胞膜而产生效应。
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| 关 键 词： | RNA．肿瘤；白血病；淋巴瘤；伴刀豆球蛋白A |
INHIBITON OF LOW-MOLECULAR RNA IN COMBINATION OF CONCANAVALIN A WITH RECEPTOR OF J6-1 CELL MEMBRANE |
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| Bi Fuyong,Lu Jinming. INHIBITON OF LOW-MOLECULAR RNA IN COMBINATION OF CONCANAVALIN A WITH RECEPTOR OF J6-1 CELL MEMBRANE[J]. Acta Academiae Medicinae Wannan, 1994, 0(3) |
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| Authors: | Bi Fuyong Lu Jinming |
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| Abstract: | The Low-Molecular RNA Extracted from brukitt lymphosarcoma namalva cells was cultinated in J6-1 cell suapension for 72 hours,and then was mixed with fluoresceinated concanavalin A.After incubation for 15 minutes of the cells of capped fluoresceinated concanavalin A and fluoresce membrane were counted. The results showed that in the experiment group there were a significant reduction of capped cells and dosage relation.It seems that the inhibitory effect of low-molecular RNA upon the cell prolireration of leukemic cells was through cell membrane. |
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| Keywords: | RNA Neoplasm Leukemia Lymphoma Concanavalin A |
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