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Short-term effects of terlipressin bolus infusion on sublingual microcirculatory blood flow during septic shock
Authors:Email author" target="_blank">Andrea?MorelliEmail author  Abele?Donati  Christian?Ertmer  Sebastian?Rehberg  Alessandra?Orecchioni  Alessandro?Di?Russo  Paolo?Pelaia  Paolo?Pietropaoli  Martin?Westphal
Institution:1.Department of Anesthesiology and Intensive Care,University of Rome, “Sapienza”,Rome,Italy;2.Department of Neuroscience, Anesthesia and Intensive Care Unit,Marche Polytechnique University,Ancona,Italy;3.Department of Anesthesiology and Intensive Care,University Hospital of Muenster,Münster,Germany
Abstract:

Purpose  

Terlipressin bolus infusion may contribute to overshooting increases in systemic vascular resistance with concomitant reductions in systemic blood flow and oxygen delivery. Whether these effects negatively impact on microcirculatory perfusion is still not known. The objective of the present study was, therefore, to elucidate the effects of a single terlipressin bolus dose of 0.5 mg on microcirculatory perfusion in patients with catecholamine-dependent septic shock.
Keywords:
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