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Spectral analysis of electroencephalogram during sleep-related apneas in pre-term and term born infants in the first weeks of life.
Authors:D Schramm  B Scheidt  A Hübler  J Frenzel  K Holthausen  O Breidbach
Affiliation:Department of Pediatrics, Friedrich-Schiller-University, Kochstrasse 2, 07740, Jena, Germany.
Abstract:OBJECTIVES: A correlation between sudden infant death syndrome (SIDS) and apnea has been discussed in a variety of studies. We analyzed polysomnographic data in 51 infants and investigated correlations between the manifestation of apneas and changes in EEG pattern. METHODS: Measurements were performed by means of the commercial polysomnographic device 'ALICE III'. Spectral analysis of certain parts of the registered EEG was performed. RESULTS: During apnea a reduction of the EEG amplitude was seen. The extent of the decrease differed slightly between the frequency bands. CONCLUSIONS: According to the widespread agreement that a lower voltage of electrical brain activity is a fundamental sign of waking up, we hypothesize that the observed change might be an immature type of arousal reaction.
Keywords:Neonatal electroencephalogram  Polysomnographic monitoring  Pre-term infants  Sudden infant death syndrome  Apnea
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