| 中学生乙型肝炎病毒前S1抗原与乙型肝炎两对半检测结果分析 |
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| 引用本文： | 韦蜀昆,景小平,黄郁荣. 中学生乙型肝炎病毒前S1抗原与乙型肝炎两对半检测结果分析[J]. 检验医学与临床, 2009, 6(9): 646-647 |
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| 作者姓名： | 韦蜀昆 景小平 黄郁荣 |
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| 作者单位： | 四川省成都市第九人民医院妇产科医院,610015;成都市第六人民医院 |
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| 摘 要： | 目的了解中学生乙型肝炎病毒（HBV）感染情况，对中学生乙型肝炎（下称乙肝）预防控制提供依据，并探讨HBV前S1抗原和乙肝两对半组合模式的关系及意义。方法采用酶联免疫吸附试验法（ELISA）对1368例中学生进行乙肝两对半和前S1抗原检测，并对检测结果进行分析。结果1368例中，健康者1337例，占97．73％，其中6项全阴者544例，单项乙肝病毒表面抗体（抗-HBs）阳性者793例。感染者31例，感染率2．27％，在感染者中大三阳和小三阳各3例，阳性率9．68％，占总检测人数0．22％，其中前S1抗原检出率与大小三阳检出率分别为3／3、2／3。表面抗原阴性者中未检出前S1抗原。男女感染率差异无统计学意义（P〉0．05）。结论两对半和前S1抗原联合检测是对中学生乙肝疫苗接种、复种和HBV携带者管理的可靠依据。前S1抗原检测是对乙肝两对半的完善和补充，对HBV感染、复制及预后有重要意义。
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| 关 键 词： | 乙肝两对半 乙肝病毒 乙肝病毒前S1抗原 酶联免疫吸附试验 |
Detection results analysis of HBV pre-S1 antigen and HBV markers in high school students |
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| WEI Shu-kun,JING Xiao-ping,HUANG Yu-rong. Detection results analysis of HBV pre-S1 antigen and HBV markers in high school students[J]. Laboratory Medicine and Clinic, 2009, 6(9): 646-647 |
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| Authors: | WEI Shu-kun JING Xiao-ping HUANG Yu-rong |
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| Affiliation: | 1. Department of Obstetrics and Gynecdology , Chengdu Ninth People＇s Hospital, Chengdu 610015, China ; 2. Chengdu Sixth People＇s Hospital, Chengdu 610051, China) |
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| Abstract: | Objective To investigate the infection of hepatitis B virus(HBV)in high school students to provide the evidence of prevention and control of the infection,and to study the relation and significance between the HBV pre-S1 antigen and HBV markers.Methods The enzyme-linked immunosorbent assay(ELISA)was carried out to detect the HBV markers and HBV pre-S1 antigen of the 1 368 high school students,then the results were analysed.Results There were 1 337 health adults in which 544 cases with all markers negative a... |
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| Keywords: | HBV markers hepatitis B virus HBV pre-S1 antigen enzyme-linked immunosorbent assay |
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