老老年高血压患者左室肥厚与血压变异性相关研究

目的：探讨老老年高血压患者左室肥厚（LVH）与血压变异性（BPV）的关系。为老老年高血压患者临床诊疗提供更多临床依据,改善心脑血管预后,提高生活质量。方法选取中国中医科学院广安门医院2012年5月-2013年6月心内科住院老老年原发性高血压患者77例,男性34例,女性43例,年龄≥80岁；根据患者左室质量指数（LVMI）将患者分成左室肥厚组与非左室肥厚组,比较两组患者的动态血压参数,血压变异性及生化指标情况。结果夜间舒张压LVH 组34例（9.74±4.33）〉非LVH 组43例（6.87±3.05）,差异有统计学意义（P〈0.01）,其他血压参数差异无统计学意义。相关性分析显示：差异有统计学意义（r=0.294, P〈0.05）。结论老老年高血压患者左室肥厚与夜间舒张压、HDL C有关,故应重视老老年高血压患者夜间舒张压波动性,及高密度脂蛋白情况,以改善并预防左心室肥厚。

Relationship between Left Ventricular Hypertrophy and Blood Pressure Variability in Very Elderly Hypertension

Objective To investigate the relationship between left ventricular hypertrophy and blood pressure variability（BPV）in very elderly hypertension.Methods Seventy seven very elderly hypertensive patients（34 males,43 females,aged ≥ 80 years old）were included.According to left ventricular mass index （LVMI）and LVH,the patients were divided into LVH groups and non LVH group.Ambulatory blood pressure parameters,blood pressure variability,and biochemical indicators were analyzed.Results SD night-time diastolic pressure in left LVH group （9.74 ±4.33）〉non LVH group （6.87 ± 3.05）,P〈0.01.Correlation analysis showed that：r=0.294,P=0.019,P〈0.05,the difference was statistically significant.Conclusion The very elderly hypertensive patients with LVH and nocturnal diastolic pressure SD were related with HDL C.