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135例原发性肝癌血清HBV标志物与AFP检测结果分析
引用本文:李益忠,陈枝俏.135例原发性肝癌血清HBV标志物与AFP检测结果分析[J].华夏医学,2006,19(3):394-395.
作者姓名:李益忠  陈枝俏
作者单位:广西中医学院附属瑞康医院,广西,南宁,530011
摘    要:目的:探讨原发性肝癌(PHC)患者乙肝病毒感染与血清甲胎蛋白(AFP)的关系。方法:应用EL ISA及放射免疫技术分别测定135例PHC患者HBV-M及AFP。结果:PHC患者感染模式分析中,HBV感染121例(89.6%),感染模式HB sA g、HB eA b、HB cA b 3项阳性(小三阳)为68例(50.4%)。135例PHC患者中,HBV-M阳性者AFP升高比例明显高于HBV-M阴性者(P<0.01)。结论:HBV是原发性肝癌发生的重要病因,在PHC患者中AFP升高与HBV感染有关。

关 键 词:原发性肝癌  乙肝病毒  甲胎蛋白
文章编号:1008-2409(2006)03-0394-02
修稿时间:2006年2月18日

Analysis of the relationship between HBV and AFP in primary hepatic carcinoma
LI Yi-zhong,CHEN Zhi-qiao.Analysis of the relationship between HBV and AFP in primary hepatic carcinoma[J].Acta Medicinae Sinica,2006,19(3):394-395.
Authors:LI Yi-zhong  CHEN Zhi-qiao
Abstract:Objective: To study the relationship between HBV and AFP in primary hepatic carcinoma(PHC).Methods: The antigen systems(HBV-M)and AFP were detected in 135 cases of PHC with the method of ELISA.Results: The model of HBV infection in patients of PHC analysis showed that 121 cases were infected by HBV(89.6%).68 cases showed "Secondary 3 positive"(HBsAg,HBeAb,HBcAb)in the infective model(50.4%).In the total 135 patients with PHC,the increase rate of AFP in the group with positive HBV-M were obviously higher than that in the negative group(P<0.01).Conclusions: HBV is an important pathogeny to PHC in which the increase of AFP has a close relationship to HBV infection.
Keywords:primary hepatic carcinoma  HBV  AFP
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