| 体外循环中血小板质和量破坏的临床初步观察 |
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| 引用本文： | 马海涛,徐五音.体外循环中血小板质和量破坏的临床初步观察[J].苏州大学学报(自然科学版),1995(2). |
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| 作者姓名： | 马海涛 徐五音 |
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| 作者单位： | 苏州医学院附属第一医院胸心外科 |
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| 摘 要： | 监测了２０例心内直视手术病人血小板计数、血小板最大聚集率（ＯＤｍａｘ）的动态变化及血小板超微结构的变化。结果提示，体外循环转流后：（１）血小板计数明显下降，转流期间维持手术前水平的６０％。转流结束后逐渐回升，术后２ｈ再度下降；（２）血小板聚集功能显著下降；（３）血小板伪足生成、畸形、破碎、脱粒和微管系统明显扩张。探讨了体外循环中血小报质量下降的机理及其临床意义．
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| 关 键 词： | 体外循环 心内直视手术 血小板 |
The Clinical Observation fo the Quality Deterioration o Platelet Arround Extracorporeal Circulation |
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| Ma Haitao,et al.The Clinical Observation fo the Quality Deterioration o Platelet Arround Extracorporeal Circulation[J].Suzhou University Journal of Medical Science,1995(2). |
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| Authors: | Ma Haitao |
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| Institution: | Department of cardiothoracic Surgery the First Hospital Affiliated to Suzhou Meducalcollege |
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| Abstract: | he article reports deterioration of characteristics and quanity of platelet. We measured thechanges of the counts,the ODmax and the ultrastructure of platelet in 20 patients undergoing open-heart surgery with cardiopulmonary bypass(CPB). The results showed that:following CPB (l )plateletcounts was decreased, maintained the 60% of preoperative level during CPBevel during CPB and increased graduallyaftar CPB,decreased again at 2 hour after operation . (2)function of aggregaton was decreased. (3)platelets crushed was increased microtubles were enlaged ;psudoopodium was; increased The:machanism was discussed and the clinical significance about the decrease of platelet qualty analysed. |
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| Keywords: | cardiopulmonary bypass(CPB) open-surgery Platelet |
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