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TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS |
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| Authors: | Ying Wang Lijing Su Matthew D Morin Brian T Jones Landon R Whitby Murali M R P Surakattula Hua Huang Hexin Shi Jin Huk Choi Kuan-wen Wang Eva Marie Y Moresco Michael Berger Xiaoming Zhan Hong Zhang Dale L Boger Bruce Beutler |
| Institution: | aCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, 75390;;bDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390;;cDepartment of Chemistry, The Scripps Research Institute, La Jolla, CA, 92037;;dDepartment of Genetics, The Scripps Research Institute, La Jolla, CA, 92037 |
| Abstract: | |
| Keywords: | neoseptins peptidomimetic compounds innate immunity proinflammatory response crystal structure |