Low daytime pulse oximetry reading is associated with nocturnal desaturation and obstructive sleep apnea in children with sickle cell anemia |
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Authors: | Spivey John F Uong Elizabeth C Strunk Robert Boslaugh Sarah E DeBaun Michael R |
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Institution: | Department of Pediatrics, Washington University School of Medicine/St. Louis Children's Hospital, St. Louis, Missouri, USA. |
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Abstract: | A retrospective medical record review was established to test the hypothesis that in children with sickle cell anemia (SCA), a daytime oxygen saturation (SpO(2)) =94% is associated with nocturnal desaturation with or without obstructive sleep apnea (OSA). Twenty children had a resting SpO(2) =94% and an abnormal polysomnogram (PSG). Seven patients had OSA and thirteen patients had nocturnal desaturation. The average daytime SpO(2) correlated with the average nighttime SpO(2) (Spearman correlation coefficient = 0.453; P = 0.045). Our results indicate that in children with SCA, a daytime SpO(2) =94% is a reasonable threshold to recommend a pulmonary evaluation, including a PSG. |
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Keywords: | nocturnal desaturation obstructive sleep apnea polysomnogram sickle cell anemia |
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