Use of high-content analysis for compound screening and target selection |
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Authors: | Rausch Oliver |
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Affiliation: | UCB Celltech, Granta Park, Great Abington, Cambridge, CB1 6GS, UK. oliver.rausch@ucb-group.com |
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Abstract: | High-content analysis (HCA) has rapidly established itself as a core technology in drug discovery for secondary cell-based screening. When combined with our knowledge of genetics, HCA can provide a powerful tool for target validation, but excitingly, HCA may also enable the increased use of cellular assays in high-throughput screening for novel drug leads. |
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