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Use of high-content analysis for compound screening and target selection
Authors:Rausch Oliver
Affiliation:UCB Celltech, Granta Park, Great Abington, Cambridge, CB1 6GS, UK. oliver.rausch@ucb-group.com
Abstract:High-content analysis (HCA) has rapidly established itself as a core technology in drug discovery for secondary cell-based screening. When combined with our knowledge of genetics, HCA can provide a powerful tool for target validation, but excitingly, HCA may also enable the increased use of cellular assays in high-throughput screening for novel drug leads.
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