| Protective effect of Apocynum venetum （罗布麻） against lipid peroxidation damage of erythrocyte membrane |
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| 引用本文： | ZhouBenhong LiuGang HuXianmin. Protective effect of Apocynum venetum （罗布麻） against lipid peroxidation damage of erythrocyte membrane[J]. 中药药理与临床, 2004, 20(3): 16-18 |
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| 作者姓名： | ZhouBenhong LiuGang HuXianmin |
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| 作者单位： | TheRenminHospitalofWuhanUniversity,Wuhan430060 |
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| 摘 要： | It is well known that lipid in membrane can maintain the integrity and function of cells. Because of the rich in saturated fatty acid, it can been attacked by radicals easily. The main damage to membrane by radicals is lipid peroxidation, it can lead to the changes in membrane‘s structures and functions. So antioxidant can effectively inhibit the lipid peroxidation damage of membrane induced by radicals.
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| 关 键 词： | 罗布麻 自由基 酶 红细胞膜脂质过氧化损伤 细胞保护 中医药疗法 药理试验 |
Protective effect ofApocynum venetum ( |
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| ZHOU Benhong,Liu Gang,Hu Xianmin. Protective effect ofApocynum venetum ([J]. Pharmacology and Clinics of Chinese Materia Medica, 2004, 20(3): 16-18 |
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| Authors: | ZHOU Benhong Liu Gang Hu Xianmin |
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| Abstract: | Objective: To investigate the protective effect of Apocynum venetum on lipid peroxidation damage of erythrocyte membrane. Methods: Model of lipid peroxidation of erythrocyte membrane was manufactured by three kinds of radicals generation systems. To set up a normal control group (NC),a model control group (MC),and four Apocynum venetum groups(A.V). Observation was made on the content of malondialdehyde (MDA). Results: Compared with MC group,all of the four Apocynum venetum groups dose-dependently inhibited the increases of MDA content in the membrane induced by xanthine - xanthine oxidase system,H 2O 2 or UV light. Conclusions: Apocynum venetum may protect erythrocyte membrane from the lipid peroxidative damage induced by radicals. |
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| Keywords: | Apocynum venetum radicals erythrocyte membrane lipid peroxidation |
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