先天性消化道畸形的影响因素分析

目的：了解佛山地区新生儿先天性消化道畸形的现状，分析影响其发生的因素。方法以佛山市17所医院作为监测医院，对2011～2014年消化道畸形的监测资料进行分析。结果共监测新生儿308530例，其中消化道畸形189例，发生率为0．61‰。消化道畸形的高危因素包括：母亲年龄大于或等于30岁、吸烟／被动吸烟、不良生育史及新生儿为男性、足月儿等。结论母亲年龄、吸烟或被动吸烟、不良妊娠史、胎儿性别、胎龄等可影响胎儿消化道畸形的发生。

Analysis of influence factors on congenital digestive tract malformation

Objective To investigate the prevalence of congenital digestive tract malformation in Foshan city ,and to investi‐gate the influential factors on congenital digestive tract malformation .Methods A total of 17 hospitals in Foshan city were moni‐tored from 2011 to 2014 ,the data of digestive tract malformation defects of neonates were analyzed .Results A total of 308 530 newborn infants were monitored ,among them ,189 cases were diagnosed with digestive tract malformation ,the incidence rate was 0 .61‰ .The high risk factors for digestive tract malformation were as follows :infant‐mother aged or more than 30 years old ,smok‐ing or passive smoking ,adverse pregnancy history of infant‐mother ,male gender of neonate and infant born at full term . Conclusion The age of infant‐mother ,smoking or passive smoking ,adverse pregnancy history of infant‐mother ,gender of neonate and gestational age could influence the incidence of gastrointestinal malformations .