武汉地区11 559名受试者跟骨骨密度检测结果分析

目的调查武汉地区不同年龄人群骨质疏松症的患病情况,为武汉地区骨质疏松症的防治提供依据。方法采用美国LUNAR PIXI骨密度检测仪,对2004年1月至2008年12月在武汉市江汉区初次行骨密度检测的11559名体检者(年龄20～99岁,男6434名,女5125名)进行右侧足跟部骨密度检查,受试者按年龄、性别和骨量情况分组,计算各组受试者的BMD值以及骨量减少和骨质疏松的发病率。结果骨量正常者的比例从20～岁组的80.5%降至80～岁组的31%。在年龄60岁的人群中,女性骨量正常者的比例较同年龄组的男性明显减少,60～、70～和80～岁组女性骨量正常的比例为36.5%、26.7%和15%,相应年龄组男性骨量正常的比例为55.6%、46.2%和38.2%。骨量减少和骨质疏松者的比例从20～岁组的18.7%和0.8%升至80～岁组的40.3%和28.7%,骨量减少的发生率从50～岁起明显升高,骨质疏松的发生率从60～岁起明显增高。在年龄60岁的人群中,女性骨量减少和骨质疏松者的比例较同年龄组男性明显增加。在60～、70～和80～岁组女性骨量减少的比例是男性的1.26、1.16和1.39倍,骨质疏松者的比例为男性的2.48、1.92倍和1.36倍。在骨量正常、骨量减少和骨质疏松组中,男性与女性受试者BMD值的差异均有统计学意义,男性BMD值均高于女性(均P0.05)。结论骨量正常者比例在20～岁组最高,并随年龄的增长而下降。骨量减少和骨质疏松者比例在20～岁组最低,并随年龄增长而升高。男性骨密度均较同年龄组女性高,女性比男性更易患骨量减少和骨质疏松症。

Clinical analysis of bone mineral density of the calcaneal region in 11 559 cases in Wuhan district

Objective To investigate the prevalence of osteoporosis in Wuhan, in order to provide scientific basis for the prevention and treatment of osteoporosis. Methods Bone mineral density （BMD） assessment of right caleaneal region （ 11 559 citizens who had medical examination in Jianghan District of the WuHan City from 2004 to 2008, including 6434 men and 5125 women, aged from 20 to 99） were measured with dual energy X-ray absorptiometer （DXA）. Prevalence of osteopenia and osteoporosis are analyzed according to BMD. Subjects were divided into groups according to different age and sex. Results The percentage of the normal bone mass decreased as the age increased, while the percentage of the osteopenia and osteoporosis was reverse. Male and female had significant differences of the BMD, no matter in which age group, in case of the same bone mass status （P 〈 0. 05）. Conclusion The prevalence of osteopenia or osteoporosis increaseed with age. The 20-year-group bad the highest percentage of normal bone mass and the lowest percentage of osteopenia and osteoporosis. Females are more liable to suffer from osteoporosis. Males had higher BMD than females.