螺旋CT在胰腺癌诊断中的应用——肿瘤-胰腺密度差的价值

目的　评价螺旋CT双期增强扫描在胰腺癌诊断中的应用价值。方法　螺旋CT双期增强扫描胰腺癌27例，先平扫，再以3ml/s速度团注对比剂150ml,分别行动脉期（注射后25s）和门脉期（注射后60～70s）扫描。并测量各扫描期肿瘤和正常胰腺组织的CT值，计算出肿瘤-胰腺密度差。结果　肿瘤的平均CT值在动脉期和门脉期分别是48±8　HU、72±6　HU，正常胰腺组织的CT值是125±18　HU、98±11　HU，肿瘤-胰腺密度差为73±21　HU、25±12　HU，二者之间有显著差别。结论　动脉期可得到最大的肿瘤-胰腺密度差值，对胰腺癌的诊断有重要的参考价值。

Application of Spiral CT for Pancreatic Adenocarcinoma: Emphasis on the Value of the Tumor-pancreas Contrast

Objective　To evaluation the application value of two-phase enhanced spiral CT in pancreatic adenocarcinoma. Methods　Two-phase enhanced spiral CT was performed in 27 cases of pancreatic adenocarcinoma. After plain CT examination, performed arterial phase（25s after infusion）and portal venous phase（60～70s after infusion）with a 150ml bolus injection of contrast material at 3ml/s. CT attenuation values of tumor and normal pancreas in all scanning phase were obtained and the tumor-pancreas contrast was calculated. Results　Mean tumor enhancement were 48±8 HU（arterial phase）and 72±6 HU（portal venous phase）, normal pancreas enhancement were 125±18 HU、98±11 HU, mean tumor-pancreas contrast was significantly differenced on arterial phase （73±21 HU）and portal venous phase （25±12 HU）. Conclusion　Excellent tumor-pancreas contrast is obtained with arterial phase scans, as such it is of significance reference value for diagnosis pancreatic adenocarcinoma.