| 广西肝细胞癌SCP-1基因的表达 |
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| 引用本文： | 黎鹏,罗国容. 广西肝细胞癌SCP-1基因的表达[J]. 华夏医学, 2005, 18(3): 317-318 |
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| 作者姓名： | 黎鹏 罗国容 |
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| 作者单位： | 广东医学院,广东,湛江,524023;广西医科大学,广西,南宁,530021 |
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| 摘 要： | 目的：检测SCP-1基因在广西人肝细胞癌中的表达情况。方法：应用SCP-1单克隆抗体。对33例肝细胞癌组织进行免疫组织化学法(SP法)检测。结果：发现28例阳性，SCP-1阳性颗粒均位于细胞质；正常的肝细胞为阴性。SCP-1在肝细胞癌组织中表达频率为84．85％(28／33)。结论：SCP-1在肝细胞癌组织中有高频率的表达，提示SCP-1将可能成为用于人肝细胞癌免疫治疗的靶抗原。
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| 关 键 词： | SCP-1基因 肝细胞癌 免疫组织化学 |
| 文章编号： | 1008-2409(2005)03-0317-02 |
| 修稿时间： | 2005-02-17 |
Study on SCP-1 expression in hepatocelluar carcinoma of Guangxi |
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| LI Peng,LUO Guo-rong. Study on SCP-1 expression in hepatocelluar carcinoma of Guangxi[J]. Acta Medicinae Sinica, 2005, 18(3): 317-318 |
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| Authors: | LI Peng LUO Guo-rong |
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| Affiliation: | LI Peng 1,LUO Guo-rong 2 1.Guangdong Medical College,Zhanjiang 524023,China, 2.Guangxi Medical University,Nanning 530021,China |
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| Abstract: | Objective:To detect the expression of SCP-1 Gene in hepatocelluar carcinoma (HCC) of Guangxi.Methods:33 cases of HCC were detected by immunohistochemical technique(SP method) using a monoclonal anti-SCP-1 antibody.Results:The antibody-positive responses were strongly in HCC tissue while the antibody-negative responses were in hepatocelluar normal tissue. The frequency of expression was 84.85%(28/33).Conclusion:These is a high frequency of expression of SCP-1 Gene in hepatocelluar carcinoma ( HCC ) of Guangxi, and which suggests that it might be a good candidate of target for immunotherapy in HCC. |
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| Keywords: | SCP-1 gene HCC immunohistochemistry |
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