| 2.4-二硝基酚对乙酰水杨酸急性毒性的影响 |
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| 引用本文： | 张富赓,胡人杰,姜卉. 2.4-二硝基酚对乙酰水杨酸急性毒性的影响[J]. 天津医科大学学报, 2002, 8(2): 189-190 |
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| 作者姓名： | 张富赓 胡人杰 姜卉 |
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| 作者单位： | 天津市医药科学研究所,天津,300070 |
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| 摘 要： | 目的：观察2．4－二硝基酚对乙酰水杨酸急性毒性的影响。方法：用简化机率法测定乙酰水杨酸与2．4－二硝基酚合用时小鼠的LD50的影响。结果：乙酰水杨酸与2．4－二硝基酚合用时，其LD50约为文献记载的1／5。结论：2．4－二硝基酚可以增加乙酰水杨酸的毒性。
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| 关 键 词： | 2.4－二硝基酚 乙酰水杨酸 急性毒性 小鼠 |
| 文章编号： | 1006-8147(2002)02-0189-02 |
| 修稿时间： | 2001-09-24 |
Effect of 2.4-Dinitrophenol on acute toxicity of acetylsalicylic acid |
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| ZHANG Fu-geng,HU Re-jie,JIANG Hui. Effect of 2.4-Dinitrophenol on acute toxicity of acetylsalicylic acid[J]. Journal of Tianjin Medical University, 2002, 8(2): 189-190 |
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| Authors: | ZHANG Fu-geng HU Re-jie JIANG Hui |
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| Abstract: | Objective: To investigate the effect of 2.4-Dinitrophenol on acute toxicity of acetylsalicylic acid in mice.Methods: The LD50 of acetylsalicylic acid with 2.4-Dinitrophenol on mice was determined by simplified probit method.Results:The LD50 in such a case is one-fifth of that of acetylsalicylic acid reported by literature.Conclusion:2.4-Dinitrophenol can increase the toxicity of acetylsalicylic acid. |
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| Keywords: | Dinitrophenol Acetylsalicylic acid Acute toxicity Mouse |
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