| 钙循环与心力衰竭 |
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| 引用本文： | 邹操,刘志华. 钙循环与心力衰竭[J]. 心血管病学进展, 2007, 28(2): 266-269 |
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| 作者姓名： | 邹操 刘志华 |
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| 作者单位： | 苏州大学附属第一医院心内科,江苏,苏州,215006 |
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| 摘 要： | 越来越多的证据表明,心肌细胞内钙循环异常在心力衰竭的发展中起着关键作用,而钙调控蛋白表达或活性的改变是钙循环异常的分子基础。现对钙调控蛋白在心力衰竭病理生理过程中的作用以及将它们作为心力衰竭治疗新靶点的可能性进行综述。
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| 关 键 词： | 钙循环 心力衰竭 钙调控蛋白 |
| 文章编号： | 1004-3934(2007)02-0266-04 |
| 修稿时间： | 2006-07-04 |
Calcium Cycling in Heart Failure |
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| ZOU Cao,LIU Zhi-hua. Calcium Cycling in Heart Failure[J]. Advances in Cardiovascular Diseases, 2007, 28(2): 266-269 |
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| Authors: | ZOU Cao LIU Zhi-hua |
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| Affiliation: | Department of Cardiology, The First Hospital Affiliated to Suzhou University, Suzhou 215006, China |
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| Abstract: | There is growing body of evidence concerning the altered intracellular Ca2 cycling that plays a key role in the development of heart failure.However,the abundance and function alterations of calcium regulatory proteins are the molecular basis of altered Ca2 cycling.This review focuses on the role of Ca2 regulatory proteins in the pathogenesis of heart failure and on the possibility of developing a new therapeutic strategy against heart failure using Ca2 regulatory proteins as a target. |
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| Keywords: | calcium cycling heart failure calcium regulatory proteins |
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