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米氮平与马普替林对抑郁症患者生活质量对照研究
引用本文:杨淑红,李聪慧,徐国银. 米氮平与马普替林对抑郁症患者生活质量对照研究[J]. 中国伤残医学, 2011, 19(8): 15-17
作者姓名:杨淑红  李聪慧  徐国银
作者单位:洛阳荣康医院,河南洛阳,471013
摘    要:目的:探讨米氮平、马普替林对抑郁症患者生活质量的影响。方法:对符合CCMD-3诊断标准的抑郁症患者随机分为2组,每组96人,分别使用米氮平、马普替林治疗2个月,用汉密顿抑郁量(HAMD)表观察患者的抑郁情绪,用药物副反应量表(TESS)评定副作用的严重程度,用生活质量综合量表(GQOLI-74)评定患者生活质量。结果:米氮平在改善患者抑郁情绪方面与马普替林相当,而米氮平副作用少且轻。2个月末,治疗前后相比,米氮平对患者的生活质量的影响,除物质生活纬度外,均明显改善(p<0.01)。马普替林组除对心理功能有提高外,对躯体功能、社会功能均无改善(p>0.05)。结论:米氮平对改善抑郁症患者生活质量优于马普替林。

关 键 词:米氮平  马普替林  生活质量  抑郁症

Comparative Study of Quality of in Depression with Mirtazapine and Maprotiline
YANG Shu-hong,LI Cong-hui,XU Guo-yin. Comparative Study of Quality of in Depression with Mirtazapine and Maprotiline[J]. Chinese JOurnal of Trauma and Disability Medicine, 2011, 19(8): 15-17
Authors:YANG Shu-hong  LI Cong-hui  XU Guo-yin
Affiliation:YANG Shu-hong,LI Cong-hui,XU Guo-yin(The second Rongkang Hospital of Henan,Luoyang,Hennan 471013,china)
Abstract:Objective:To explore the effect of qulity of life in depression with Mirtazapine and Maprotiline .Methods:The patient that consistent the diagnostic criteria of depression in CCMD-3 were randomized into two group 48 cases.The course of treatment was 2 months .Before and after the treatment,the depres-symptoms were evaluated by HAMD,the side effects were evaluated by TESS and the qulity of life were evaluated by(QOLI-74.) Results:The curative effect to improve despress symptoms in group Mirtazapine was equiv...
Keywords:Qulity of life  Depression  Mirtazapine  Maprotiline  
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