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Superagonist IL-15-Armed Oncolytic Virus Elicits Potent Antitumor Immunity and Therapy That Are Enhanced with PD-1 Blockade
Authors:Stacy J. Kowalsky  Zuqiang Liu  Mathilde Feist  Sara E. Berkey  Congrong Ma  Roshni Ravindranathan  Enyong Dai  Edward J. Roy  Zong Sheng Guo  David L. Bartlett
Affiliation:1. Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;2. UPMC Hillman Cancer Center, Pittsburgh, PA, USA;3. Department of Surgery, CCM/CVK, Charité - Universitaetsmedizin Berlin, Berlin, Germany;4. Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA
Abstract:
Keywords:oncolytic virus  vaccinia virus  IL-15  superagonist  antitumor immunity  immune checkpoint blockade  immunotherapy  efficacy  oncolytic vicotherapy
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