| DDP和沙培林胸腔用药联合NP方案对肺癌合并恶性胸腔积液近远期疗效的观察 |
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| 引用本文： | 程伏林,陈家宽.DDP和沙培林胸腔用药联合NP方案对肺癌合并恶性胸腔积液近远期疗效的观察[J].肿瘤防治研究,2003,30(3):223-224. |
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| 作者姓名： | 程伏林 陈家宽 |
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| 作者单位： | 430070,武汉大学中南医院肿瘤研究所 |
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| 摘 要： | 目的 观察DDP和沙培林胸腔用药联合NP方案全身化疗治疗肺癌合并恶性胸腔积液的近远期疗效。方法 32例肺癌合并恶性胸腔积液患者随机分成两组 ,A组 :1 6例 ,胸膜腔内单用药组 ,使用DDP和沙培林 ,B组 :1 6例 ,胸膜腔内用药并联合使用NP(NVB +DDP)方案全身化疗。结果 ①A、B两组胸水控制短期有效率分别为 75 %和 87.5 % ,总有效率为 81 .3% ,两组比较无显著性差异 (P >0 .0 5 )。②A组1年、2年生存率分别为 4 3.75 %和 6 .2 5 % ,B组分别为 6 2 .5 %和 31 .2 5 % ,两组比较有显著性差异 (P <0 .0 5 )。结论 DDP和沙培林胸腔用药能有效控制胸水 ;在胸腔用药的基础上继用NP方案全身化疗有助于提高肺癌合并恶性胸腔积液患者的生存率
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| 关 键 词： | 肺癌合并恶性胸腔积液 沙培林 NVB |
| 文章编号： | 1000-8578(2003)03-0223-02 |
| 收稿时间： | 2001-8-15 |
| 修稿时间： | 2001年8月15日 |
Clinical observation of combination chemotherapy and intrapleural injection of Sapylin and Cisplatin on malignant pleural effusions |
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| CHENG Fu lin,CHEN Jia kuan Cancer Institute,Zhongnan Hospital,Wuhan University,Wuhan ,China.Clinical observation of combination chemotherapy and intrapleural injection of Sapylin and Cisplatin on malignant pleural effusions[J].Cancer Research on Prevention and Treatment,2003,30(3):223-224. |
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| Authors: | CHENG Fu lin CHEN Jia kuan Cancer Institute Zhongnan Hospital Wuhan University Wuhan China |
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| Institution: | CHENG Fu lin,CHEN Jia kuan Cancer Institute,Zhongnan Hospital,Wuhan University,Wuhan 430070,China |
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| Abstract: | Objective To study the curative effect of intrapleural injection of Sapylin and Cisplatin in combination with NP regimen adjuvant chemotherapy. Methods 32 patients were divided into two Groups:16 patients were treated with intrapleural injection of Sapylin and Cisplatin(A gronp),16 patients were treated with intrapleural injection of the same drugs in combination with NP regimen adjuvant chemotherapy(NVB+DDP)(B group). Results ① The short term effective rates of A and B group were 75% and 87.5% resp... |
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| Keywords: | Malignant pleural effusion Sapylin NVB |
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