Hematometrocolpos in an adolescent female treated for pelvic Ewing sarcoma |
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Authors: | Gaillard Pamela Krasin Matthew J Laningham Fred H Hoffer Fredric A Davidoff Andrew M Spunt Sheri L Smiley Linda Skapek Stephen X |
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Institution: | Department of Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. |
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Abstract: | Radiation therapy is often used to achieve local control of pelvic Ewing sarcoma in children. The effects of radiation on the female reproductive tract have been well documented in adults with gynecological malignancies, but the long-term consequences of pelvic radiation in pre-pubertal or adolescent girls are not as well described. We report a case of hematometrocolpos developing in an adolescent previously treated with chemotherapy and radiation therapy for pelvic Ewing sarcoma. We describe the clinical presentation, radiographic features, gross pathology, treatment strategies, outcome, as well as putative predisposing factors and preventative interventions. |
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Keywords: | Ewing sarcoma hematometrocolpos late effects of cancer therapy |
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