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密达利杀灭湖北钉螺效果的研究
引用本文:朱丹,周晓农,张世清,张功华,刘和香,吕大兵,蔡国英,倪全珍,操治国,吴维铎. 密达利杀灭湖北钉螺效果的研究[J]. 中国寄生虫学与寄生虫病杂志, 2006, 24(3): 200-203
作者姓名:朱丹  周晓农  张世清  张功华  刘和香  吕大兵  蔡国英  倪全珍  操治国  吴维铎
作者单位:1. 中国疾病预防控制中心寄生虫病预防控制所,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,上海,200025
2. 安徽省寄生虫病防治研究所,芜湖,241000
摘    要:目的 实验室和现场试验评价密达利(META-Li, 40%四聚乙醛水乳剂)杀灭湖北钉螺的效果。 方法 室内:采用泥缸喷洒法、烧杯浸杀法和三角沉淀杯上爬法,用敲击法观察不同时间、不同浓度密达利对湖北钉螺的杀灭和抑制上爬作用。现场:选择安徽省芜湖县草滩进行现场喷洒试验,密达利剂量为1、2和4 g/m2,设氯硝柳胺药物对照剂量为1 g/m2和清水空白对照组,观察施药后3、7和15 d检查钉螺存活情况。 结果 室内喷洒试验:24、48和72 h的半数致死剂量(LD50)分别为0.78、0.44和0.46 g/m2;室内浸杀试验:24、48、72 h的半数致死浓度(LC50)分别为44.4、27.4和24.8 mg/L;24 h抑制钉螺上爬半数有效浓度(EC50)为5.86 mg/L。现场喷洒试验:密达利2 g/m2喷洒后7 d钉螺死亡率大于90%,灭螺效果和氯硝柳胺1 g/m2相当(P>0.05)。 结论 密达利室内及现场喷洒灭螺效果明显,有抑制钉螺上爬作用。

关 键 词:密达利  四聚乙醛  钉螺  杀螺剂
文章编号:1000-7423(2006)-03-0200-04
收稿时间:2006-02-06
修稿时间:2006-02-06

Study on the Molluscicidal Effect of META-Li Against Oncomelania hupensis
ZHU Dan,ZHOU Xiao-nong,ZHANG Si-qing,ZHANG Gonghua,LIU He-xiang,LU Da-bing,CAI Guo-ying,NI Quan-zheng,CAO Zhi-guo,WU Wei-duo. Study on the Molluscicidal Effect of META-Li Against Oncomelania hupensis[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2006, 24(3): 200-203
Authors:ZHU Dan  ZHOU Xiao-nong  ZHANG Si-qing  ZHANG Gonghua  LIU He-xiang  LU Da-bing  CAI Guo-ying  NI Quan-zheng  CAO Zhi-guo  WU Wei-duo
Affiliation:1 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China; 2 Anhui Institute of Parasitic diseases, Wuhu 241000, China
Abstract:Objective To evaluate the molluscicidal effect of the META-Li(40% META liquid formulation) against Oncomelania snails in laboratory and field. Methods The experiment of META-Li against the snails by spraying, immersion and climbing-inhibition test was carried out in laboratory. Spray method was performed in the field to compare with the wettable powder of 50% niclosamide ethanolamine salt. Results In laboratory, the LC50 of META-Li by spraying for 1, 2, 3 days was 0.78, 0.44 and 0.46 g/m2 respectively; by immersion method for 1, 2, 3 days, it was 44.4, 27.4 and 24.8 mg/L respectively. When sprayed with active ingredient 2 g/m2 of META-Li in the field, the snail death rate was above 90% after 7 days, similar to that of niclosamide. Conclusion META-Li shows high molluscicidal and climbing-inhibition effect on Oncomelania snails.
Keywords:Meta-Li   Metaldehyde   Oncomelania hupensis   Molluscicide
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