| 糖尿病患者自由基清除障碍机理探讨 |
| |
| 引用本文： | 唐尧,田红梅,刘少华,王尧,赵瑞革,赵青莉,唐琴华,何岳文.糖尿病患者自由基清除障碍机理探讨[J].东南大学学报(医学版),1993(3). |
| |
| 作者姓名： | 唐尧 田红梅 刘少华 王尧 赵瑞革 赵青莉 唐琴华 何岳文 |
| |
| 作者单位： | 附属医院内分泌科，附属医院内分泌科，附属医院内分泌科，附属医院内分泌科，附属医院内分泌科，附属医院内分泌科，南京铁道医学院附属医院检验科，南京铁道医学院附属医院检验科 南京 210009，进修医师 南京 210009，南京 210009，南京 210009，进修医师 南京 210009，进修医师 南京 210009，南京210009，南京210009 |
| |
| 摘 要： | 作者测定了46例 NIDDM 患者和55例正常人的血清过氧化脂质(LPO)、硒(se)、维生素 E(VE)含量以及超氧化物歧化酶(SOD)的活性。结果发现,NIDDM 患者血清LPO 含量增高,VE 减低,SOD 活性下降,Se 无变化。提示 NIDDM 患者体内存在的自由基损伤和清除障碍主要是由 SOD 活性降低和 VE 含量减少引起的,与 Se 含量无关。
|
| 关 键 词： | 非胰岛素依赖型糖尿病 自由基 过氧化脂质 硒 维生素 E 超氧化物歧化酶 糖尿病 |
STUDY ON THE METABOLIC ABNORMALITY OF FREE RADICALS IN NIDDM |
| |
| Tang Yao Tian Hongmei Liu Shaohua Wang Yao Zhao Ruige Zhao Qingli.STUDY ON THE METABOLIC ABNORMALITY OF FREE RADICALS IN NIDDM[J].Journal of Southeast Univ: Medical Sci Ed,1993(3). |
| |
| Authors: | Tang Yao Tian Hongmei Liu Shaohua Wang Yao Zhao Ruige Zhao Qingli |
| |
| Abstract: | The levels of serum lipoperoxides(LPO),selenium(Se),vitamin E(VE)and activity of su- peroxide dismutase(SOD)were measured in 46 NIDDM patients and 55 healthy subjects.The re- sults showed that the level of VE and activity of SOD were significantly lower in NIDDM patients as compared with those in the controls.The results suggested that the metabolic abnormality of free radicals in NIDDM paticnts has relations with the decrease of VE content and SOD activity. |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
