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Effects of radiotherapy determined by11C-methyl-l-methionine positron emission tomography in patients with primary cerebral malignant lymphoma |
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| Authors: | J. Sawataishi K. Mineura T. Sasajima M. Kowada A. Sugawara F. Shishido |
| Affiliation: | (1) Neurosurgical Service, Akita University Hospital, Akita, Japan;(2) Department of Neurosurgery, Nakadori Hospital, Akita, Japan;(3) Department of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita, Akita, Japan |
| Abstract: | Summary Two cases of histologically proven primary cerebral malignant lymphoma were examined serially with positron emission tomography (PET) using11C-methyl-l-methionine (11C Met). Lesions delineated by11C Met accumulation extended beyond enhancing areas on either X-ray computed tomography (CT) or magnetic resonance imaging. High uptake of11C Met accurately showed biologically active and residual tumours, at a time when disappearance of a contrast-enhancing lesion on CT seemed to indicate involution. PET provides valuable information on the extent of tumour and assessment of radiotherapy in malignant lymphoma. |
| Keywords: | Cerebral malignant lymphoma 11C-methyl- font-variant:small-caps" >l-methionine Positron emission tomography Radiotherapy |
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