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Effects of radiotherapy determined by11C-methyl-l-methionine positron emission tomography in patients with primary cerebral malignant lymphoma
Authors:J Sawataishi  K Mineura  T Sasajima  M Kowada  A Sugawara  F Shishido
Institution:(1) Neurosurgical Service, Akita University Hospital, Akita, Japan;(2) Department of Neurosurgery, Nakadori Hospital, Akita, Japan;(3) Department of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita, Akita, Japan
Abstract:Summary Two cases of histologically proven primary cerebral malignant lymphoma were examined serially with positron emission tomography (PET) using11C-methyl-l-methionine (11C Met). Lesions delineated by11C Met accumulation extended beyond enhancing areas on either X-ray computed tomography (CT) or magnetic resonance imaging. High uptake of11C Met accurately showed biologically active and residual tumours, at a time when disappearance of a contrast-enhancing lesion on CT seemed to indicate involution. PET provides valuable information on the extent of tumour and assessment of radiotherapy in malignant lymphoma.
Keywords:Cerebral malignant lymphoma  l-methionine" target="_blank">11C-methyl-l-methionine  Positron emission tomography  Radiotherapy
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