| 脑苷肌肽注射液治疗新生儿缺氧缺血性脑病疗效观察 |
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| 引用本文： | 魏红梅.脑苷肌肽注射液治疗新生儿缺氧缺血性脑病疗效观察[J].中国实用医药,2009,4(19):29-30. |
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| 作者姓名： | 魏红梅 |
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| 作者单位： | 河南省漯河市第二人民医院儿科,462000 |
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| 摘 要： | 目的观察脑苷肽注射液治疗新生儿缺氧缺血性脑病的疗效。方法从2005年8月至2007年10月对我院NICU收治的60例新生儿HIE患儿随机分成2组，治疗组（n=30）使用脑苷肌肽治疗；对照组（n=30）使用胞二磷胆碱或1，6-二磷酸果糖治疗，通过比较两组患儿临床神经症状恢复时间及新生儿行为神经评分（NBNA）来判断药物的疗效。结果脑苷肌肽与胞二磷胆碱或1，6-二磷酸果糖治疗新生儿HIE的疗效差异无显著性意义（P〉0．05），均能在7-10天使神经症状恢复正常，在生后2周NBNA评分绝大多数在正常范围内。结论早期应用脑苷肌肽治疗新生儿HIE有良好疗效。
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| 关 键 词： | 脑苷肌肽 缺氧缺血性脑病 新生儿行为神经评分 治疗 |
An observation of the effect of cattle encephalon glycoside and ignotin injection in treating hypoxic-ischemic encephalopathy |
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| WEI Hong-mei.An observation of the effect of cattle encephalon glycoside and ignotin injection in treating hypoxic-ischemic encephalopathy[J].China Practical Medical,2009,4(19):29-30. |
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| Authors: | WEI Hong-mei |
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| Institution: | WEI Hoag-mei. (Department of Pediatrics, No. 2 People＇ s Hospital, Luo he , He nan , 462000, China) |
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| Abstract: | Objective To observe curative effect of cattle encephalon glycoside and ignotin injection (GM1 made in China) on neonatal hypoxic-ischemic encephalopathy (HIE). Methods 60 cases neonates with HIE were randomly divided into two groups :GM1 treated group (n=30) and nicholin or fructose-1,6-diphosphate (FDP) treated control group (n=30) , The recover time of abnormal neurological symptoms and signs and the score of neonatal behavioral neurological assessment (NBNA) was evaluated in acute phase of HIE. Results The recover time of abnormal neurological symptoms and signs and the score of NBNA there wasn't significant difference between GM1 treated group and control group (P>0.05).Conclusion GM1 administ ration has early benefit to the patients with HIE |
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| Keywords: | GM1 Hypoxic-ischemic encephalopathy Neonatal behavioral neurological assesssment Treatment |
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