阴茎勃起功能障碍的药物治疗进展

阴茎勃起功能障碍 (ED)是一种影响男性健康的常见疾病。ED的治疗方法很多 ,口服药物已成为一线治疗方法 ,其中包括作用于周围和中枢神经系统的药物、激素类和中药等。西地那非、阿朴吗啡和育亨宾是目前治疗ED的 3种首选口服药物。二线治疗方法有阴茎海绵体内注射疗法、经尿道给药和经阴茎皮肤给药等。作者就ED的最新药物治疗进展作一综述。

Advances on pharmacotherapy for erectile dysfunction

It is reported that plenty of men,especially the aged,have been bothering in penile erectile dysfunction(ED).There are series of treatments for ED.Oral erectogenic agents have become the first-line treatment options,including drugs that act on the central and peripheral nervous systems,testosterone,traditional Chinese medicine and so on.Sidenafil,apomorphine and yohimbine are the only three oral therapies currently available for the treatment of this disorder.The second therapy includes intracavernosum injection,transurethral medications,transdermal medications etc.Intracavernosum injection of PGE 1 is an effective approach at the present.With the rapid understanding of erectile physiology and etiology of ED and the introduction of new effective oral agents,the future of pharmacotherapy for ED will extend.In this review,we have highlighted the advances in current treatments and therapeutic approaches in male erectile dysfunction.