小儿肺炎支原体合并EB病毒感染100例分析

目的探讨肺炎支原体合并EB病毒感染患儿的临床特点,为临床诊治提供借鉴。方法收集住院治疗的支原体肺炎合并EB病毒感染患儿100例作为观察组,同期支原体肺炎患儿85例作为对照组,比较两组患儿的临床特点和实验室检查结果,并进行比较分析。结果观察组平均发热时间和住院时间较对照组明显延长,观察组异形淋巴细胞比例,2个肺叶以上受侵犯以及合并胸腔积液,其他脏器损伤等发生率均高于对照组,两组比较差异有统计学意义;观察组外周血白细胞高于对照组(P0.05);淋巴细胞和异淋细胞升高明显(P0.01),两组差异有显著性;血红蛋白含量及血小板较对照组偏低(P0.05);ALT、AST、LDH和CK-MB两组具有明显的差异。结论肺炎支原体感染合并EB病毒感染比例较高,其器官受累严重,较单纯肺炎支原体感染患儿临床症状严重,其实验室检查指标改变明显。

Clinical Analysis of Mycoplsama Pneumoiae Infection Complicated with EBV Infection in 100 Patients

Objective To analyze the clinical characteristics of mycoplsama pneumoiae（ MP） infection complicated with Epstein-Barrvirus（ EBV） infection. Methods The CBC,myocardial enzymes,liver function and Clinical characteristics of 185 children admitted from January 2010to December 2012 were analyzed retrospectively,including 100 children with diagnosed MP infection complicating with EBV infection,85 with MP infection. Results Abnormal lymphocytes percent with diagnosed MP infection complicating with EBV infection were high than the control. The time of fever,the time of staying hospital,The cases above 2 lobe of lungs damagedand the cases with pleural effusionwere high than the control. The quantity of peripheral blood leukocytes in children with mixed infections was higher than that of EB infection group and MP infection group（ P〈0. 05）; the rate of lymphocytes and atypical lymphocyte increased significantly（ P〈0. 01）,but showed no significant differences compared to EB infection; hemoglobin content and platelets was lower compared with two control groups（ P〈0. 05）; the level of ALT,AST and LDH in mixed infection group were significantly higher than that of the MP infection group（ P〈0. 05）,but showed no significant difference compared to EB infection group; CK-MB increased significantly compared with two control groups（ P〈0. 05）. complicating with EBV infection. Conclusion The rate of mycoplsama pneumoiae infection complicating with EBV infection is high. That can increase the damage of lungs. To mycoplsama pneumoiae infection. We should examine EBV antibodies timely and give the right treatment.