| 复方地蒽酚软膏的质量控制 |
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| 引用本文： | 杨宗学,陈丽. 复方地蒽酚软膏的质量控制[J]. 解放军药学学报, 2010, 26(3): 230-231. DOI: 10.3969/j.issn.1008-9926.2010.03.014 |
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| 作者姓名： | 杨宗学 陈丽 |
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| 作者单位： | 解放军第149医院药剂科,江苏连云港,222042 |
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| 基金项目： | 2009年度南京军区医学科技创新经费资助项目 |
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| 摘 要： | 目的对复方地蒽酚软膏剂进行质量控制。方法采用紫外可见分光光度法测定地蒽酚的含量,碘量法测定硫的含量,络合法测定氧化锌的含量。结果地蒽酚在3.2～11.2μg/ml范围内,具有良好的线性关系,r=0.9998,平均加样回收率为99.51%,RSD为0.61%。碘量法测定硫的含量及络合法测定氧化锌的含量,处方中的组分互不干扰。结论该制剂稳定,处方工艺设计合理,质量控制方法简便、可靠、易行。
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| 关 键 词： | 地蒽酚 硫 氧化锌 复方制剂 质量控制 |
The Quality Control of Compound Anthralin Ointment |
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| YANG Zong-xue,CHEN Li. The Quality Control of Compound Anthralin Ointment[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 2010, 26(3): 230-231. DOI: 10.3969/j.issn.1008-9926.2010.03.014 |
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| Authors: | YANG Zong-xue CHEN Li |
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| Affiliation: | Department of Pharmacy,Hospital 149 of PLA,Lianyungang 222042,China |
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| Abstract: | Objective To study quality control methods for Compound anthralin ointment.Methods The content of anthralin was measured using UV-visible spectrophotometry,sulfur content measured with the iodometric method and zinc oxide content measured with compleximetry.Results Anthralin had a good linear relationship within the range of 3.2-11.2 μg/ml;r=0.9998.Conclusion The preparation is stable,process design is reasonable,and the quality control method is simple,reliable and easy. |
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| Keywords: | anthralin sulfur zinc oxide compound preparation quality control |
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