| 卡介菌多糖核酸对T细胞集落形成及IL－2受体表达的调节作用 |
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| 引用本文： | 金一平,方建珍,高洁生. 卡介菌多糖核酸对T细胞集落形成及IL－2受体表达的调节作用[J]. 现代免疫学, 1994, 0(1) |
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| 作者姓名： | 金一平 方建珍 高洁生 |
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| 作者单位： | 湖南医科大学第二附属医院 |
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| 摘 要： | 本文用体外实验方法，研究ＢＣＧ－ＰＳＮ对ＴＬ－ＣＦｕ形成及ＩＬ－２Ｒ表达的调节作用。结果表明，当ＢＣＧ－ＰＳＮ浓度为８０μｇ／ｍｌ时，ＴＬ－ＣＦＵ形成及ＩＬ－２Ｒ表达均达到峰值，对ＩＬ－２Ｒ表达的调节于７２ｈ达最高水平，并且．ＴＬ－ＣＦＵ形成和ＩＬ－２Ｒ表达均显著高于对照组。提示ＢＣＧ－ＰＳＮ能增进Ｔ淋巴细胞功能。
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| 关 键 词： | 卡介菌多糖核酸，免疫调节，T淋巴细胞集落形成单位，白细胞介素2受体 |
REGULATORY EFFECTS OF BCG-PSN ON T CELL COLONY FORMATION AND EXPRESSION OF INTERLEUKIN-2 RECEPTOR |
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| Jin Yiping,Fan Jianzheng,Gao Jieshen. REGULATORY EFFECTS OF BCG-PSN ON T CELL COLONY FORMATION AND EXPRESSION OF INTERLEUKIN-2 RECEPTOR[J]. Current Immunology, 1994, 0(1) |
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| Authors: | Jin Yiping Fan Jianzheng Gao Jieshen |
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| Abstract: | The immunoregulatory action of polysaccharide-nucleic acid fraction fromBacillus-Calmatte-Guerin(BCG-PSN)on T-cell colony forming units(TL-CFU)andInterleukine 2 receptor(IL-2R)expression were studied in vitro. The results showedthat the number of TL-CFU and IL-2R positive cells were significantly higher inBCG-PSN activated group than those in controls.This suggested that BCG-PSN couldpromote T lymphocyte function and increase the cellular immunity. |
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| Keywords: | BCG-PSN T lymphocyte activity T-Lymphocyte Colony Forming Units Interleukine 2 receptor Immunoregulation |
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