角膜塑型术后眼波前像差变化

目的 探讨角膜塑型术后眼波前像差变化及其影响因素，了解第3代角膜塑型术对视觉质量的影响。方法 对进行角膜塑型术的21例（42眼）进行了前瞻性临床研究，将角膜塑型术术前及术后达最佳裸眼视力时的眼波前像差情况作测量与比较。检查结果通过Matlab软件分析．直接获取35项Zemike系数及每阶Zemike系数的RMS值。结果 角膜矫型术后总像差，第3、第4、第5、第7阶RMS值较术前增加，且差异有显著性（P〈0．05）。第2、第6阶RMS值较术前增加，但差异无显著性（P〉0．05）。结论 角膜塑型术后眼的像差增加，降低了视觉质量。角膜光学区直径的缩小以及偏离、角膜表面的非规则性增加，角膜非生理形态的改变等是导致像差增加的原因。

Changes in aberrations following orthokeratology

Objective To study the wavefront aberrations induced by orthokeratology and the changes in aberrations following treatment.Methods Orthokeratology was performed to correct the refractive errors of 42 eyes of 21 patients.Wavefront aberrations were measured with a subjective aberrometer(Suzhou Brite Eye Model WFA 1000) before treatment and at the time the best uncorrected visual acuity was obtained following orthokeratology.Three measurements were obtained for each condition,and RMS values for overall wavefront aberrations and each order of the Zernike aberrations were analyzed.Results Overall,wavefront aberrations and the RMS from the 3rd to the 5th and the 7th order of Zernike aberrations were significantly greater after treatment than before treatment(P<0.05).However,there was no difference between the two conditions in the RMS of the 2nd and 6th order of Zernike aberrations.Conclusion Orthokeratology can cause an increase in wavefront aberration in the human eye.