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狼疮性肾炎血清酶的变化及临床意义
引用本文:杜艺,宋泽开,陈孟华.狼疮性肾炎血清酶的变化及临床意义[J].宁夏医科大学学报,2000,22(3):170-171,174.
作者姓名:杜艺  宋泽开  陈孟华
作者单位:宁夏医学院附属医院肾内科!银川750004
摘    要:目的:研究狼疮性肾炎(LN)患者血清酶的变化及临床意义。方法:通过全自动生化分析仪检验34例LN患者及30名健康体检者血中8种血清酶。结果:LN组较健康组LDH、HBDH、AST、GGT(p〈0.01)、ALP(p〈0.05)明显升高,均有显著性意义,而CK、AMY和ALT(p〉0.05)无显著性意义。LDH和HBDH(p〈0.0005)之间有高度相关性。结论:LDH、HBDH、AST、GGT和A

关 键 词:狼疮性肾炎  血清酶  同工酶

The Clinical Implication of Seroenzyme Changes in Patient With Lupus Nephritis
DU Yi,SONG Ze-kai,CHEN Meng-hua.The Clinical Implication of Seroenzyme Changes in Patient With Lupus Nephritis[J].Journal of Ningxia Medical College,2000,22(3):170-171,174.
Authors:DU Yi  SONG Ze-kai  CHEN Meng-hua
Abstract:Objective: To study the clinical implication of seroenzyme changes in patient with lupus nephritis (LN). Methods: Eight serum enzymes of 34 patients with LN and 30 normal persons were examined by automatic biochemical analyzer. Results: Compared with normal person, the serum levels of LDH, HBDH, GOT, GGTP and ALP were significantly increased and CK, AMY and ALT had no significant difference in patients with LN. This trial showed that LDH had a strong positive correlation with HBDH. Conclusion: Elevation of the serum LDH, HBDH,GOT, GGTP and ALP levels may be used as a better diagnosis predictor for LN. Among all organs, the kidney is the richest in LDH content. The LDH is highly sensitive and the HBDH is the most specific. Both LDH and HBDH can increase diagnostic reliability of LN.
Keywords:lupus nephritis  serum enzyme  isozyme
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