| Determinantion and evaluation of antisperm antibodies and seminal immunosuppressive material in recurrent aborting couples |
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| 引用本文： | 颜建华,黄宇烽,庄恭南,武建国. Determinantion and evaluation of antisperm antibodies and seminal immunosuppressive material in recurrent aborting couples[J]. 医学研究生学报, 1990, 0(4) |
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| 作者姓名： | 颜建华 黄宇烽 庄恭南 武建国 |
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| 作者单位： | Yan Jian-hua Huang Yu-feng Zhuang Gong-nan Wu Jian-guo Department of Clinical Immunology，Jinling Hospital，Nanjing，China |
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| 摘 要： | Circulating antisperm antibodies (AsAb) and immunosuppressive material in seminal plasma (SPIM)were determined by solid-phase enzyme staining assay and anticomplement test respectively in 686 patients with abortion (including 285 couples) . 241 fertile couple served as control. It's found that the positive rate of AsAb in infertile patients was significantly higher than that in fertile control,being 36.6% vs 3.3% (P<0.001). AsAb was even more offen detected in recurrent aborting patients. Male patients whose spouses aborted 2-6 fetuses had significantly less SPIM than control, sperm count and sperm motility were also significantly decreased. But the incidence of pyospermia was significantly greater than that in control. It is concluded that AsAb and SPIM have played an important role in the development of recurrent abortions.
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Determinantion and evaluation of antisperm antibodies and seminal immunosuppressive material in recurrent aborting couples |
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| Yan Jian-hua Huang Yu-feng Zhuang Gong-nan Wu Jian-guo. Determinantion and evaluation of antisperm antibodies and seminal immunosuppressive material in recurrent aborting couples[J]. Bulletin of Medical Postgraduate, 1990, 0(4) |
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| Authors: | Yan Jian-hua Huang Yu-feng Zhuang Gong-nan Wu Jian-guo |
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| Affiliation: | Yan Jian-hua Huang Yu-feng Zhuang Gong-nan Wu Jian-guo Department of Clinical Immunology,Jinling Hospital,Nanjing,China |
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| Abstract: | Circulating antisperm antibodies (AsAb) and immunosuppressive material in seminal plasma (SPIM)were determined by solid-phase enzyme staining assay and anticomplement test respectively in 686 patients with abortion (including 285 couples) . 241 fertile couple served as control. It's found that the positive rate of AsAb in infertile patients was significantly higher than that in fertile control,being 36.6% vs 3.3% (P<0.001). AsAb was even more offen detected in recurrent aborting patients. Male patients whose spouses aborted 2-6 fetuses had significantly less SPIM than control, sperm count and sperm motility were also significantly decreased. But the incidence of pyospermia was significantly greater than that in control. It is concluded that AsAb and SPIM have played an important role in the development of recurrent abortions. |
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| Keywords: | Abortion Habitual Antisperm Antibody Seminal Immunosuppressive Material |
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