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Hepatitis C genotype change after transplantation utilizing hepatitis C positive donor organs
Authors:R Adekunle  S Jonchhe  B Ravichandran  E Wilson  J Husson
Institution:1. Department of Medicine, University of Maryland Medical Center, Baltimore, MD, USA;2. University of Maryland School of Pharmacy, Baltimore, MD, USA;3. Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA
Abstract:A shortage in organs for transplantation has led to the increased use of hepatitis C (HCV) infected donor organs for solid organ transplant recipients infected with HCV. However, the donor HCV genotype is not routinely checked or known prior to transplant. Here, we report 4 cases of genotype conversion after transplantation in patients receiving HCV infected donor organs. This change in genotype may potentially impact HCV progression as well as treatment choice for these patients.
Keywords:genotype  hepatitis C  transplantation
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