Aldosterone binding with corticosteroid brain receptors in rats: Effect of behavioral typology and stress |
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| Authors: | Yu A Akimov M V Onufriev N A Lazareva N V Gulyaeva |
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| Institution: | (1) Laboratory of Functional Biochemistry of the Nervous System, Institute of Higher Nervous Activity and Neurophysiology, the Russian Academy of Sciences, Moscow |
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| Abstract: | Differences in3H-aldosterone binding with hippocampus cytosol receptors were found to be dependent on the behavioral type of male Wistar
rats in the “emotional resonance” test. These differences were not observed in the cytosol analysis of the remaining part
of the brain. Control rats and rats subjected to short-term stress by painful electrical stimulation showed a long-term drop
of3H-aldosterone binding with hippocampus cytosol in active as compared to passive animals preferring a closed space.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, N
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7, pp. 49–51, July, 1995
Presented by I. P. Ashmarin, Member of the Russian Academy of Medical Sciences |
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| Keywords: | corticosteroid receptors aldosterone brain hippocampus stress individual behavior |
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