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胃癌患者血清中胃癌相关细胞因子检测及其在胃癌诊断中的应用价值
引用本文:孙瑞营,李洋,赵旭,曲林琳,续薇,张蕴莉.胃癌患者血清中胃癌相关细胞因子检测及其在胃癌诊断中的应用价值[J].吉林大学学报(医学版),2020,46(6):1274-1282.
作者姓名:孙瑞营  李洋  赵旭  曲林琳  续薇  张蕴莉
作者单位:锦州医科大学附属第一医院检验科,辽宁 锦州 121000
吉林大学第一医院检验科,吉林 长春 130021
吉林大学第一医院肝胆胰内科,吉林 长春 130021
基金项目:国家自然科学基金青年基金资助课题(81903051);国家自然科学基金面上项目资助课题(81672106)
摘    要:目的检测胃癌患者血清中17种胃癌相关细胞因子的水平,研究其与miR-10b水平的相关性,筛选在实验诊断中对胃癌诊断有意义的肿瘤标志物并探讨其对胃癌诊断的应用价值。

关 键 词:胃肿瘤  细胞因子  miRNA-10b  巨噬细胞炎性蛋白3α  肿瘤标志物  
收稿时间:2020-04-23

Detection of serum levels of gastric cancer-related cytokines and their clinical significances in diagnosis of gastric cancer
Ruiying SUN,Yang LI,Xu ZHAO,Linlin QU,Wei XU,Yunli ZHANG.Detection of serum levels of gastric cancer-related cytokines and their clinical significances in diagnosis of gastric cancer[J].Journal of Jilin University: Med Ed,2020,46(6):1274-1282.
Authors:Ruiying SUN  Yang LI  Xu ZHAO  Linlin QU  Wei XU  Yunli ZHANG
Institution:Departement of Clinical Laboratory,First Affiliated Hospital,Jinzhou Medical University,Jinzhou 121000,China
Department of Clinical Laboratory,First Hospital,Jilin University,Changchun 130021,China
Department of Hepatobiliary and Pancreatic Medicine,First Hospital,Jilin University,Changchun 130021,China
Abstract:ObjectiveTo detect the expression levels of 17 kinds of gastric cancer-related cytokines in serum of the gastric cancer patients and study their correlations with miR-10b level, and to screen the tumor markers which were meaningful for the diagnosis of gastric cancer and to explore their application values in diagnosis of gastric cancer.
Keywords:stomach neoplasms  cytokine  miR-10b  macrophage inflammatory protein -3α  tumor marker  
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